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(LC-MS/MS)

Biomarker Assays

Our bioanalytical expertise lies in challenging and specialized PD biomarkers analyses. We have a diverse range of established biomarker assays, in addition to the ability to build new targeted workflows. We deliver the highest quality data and we tackle any stability, interference issues that are inherent to biomarker assessments, using surrogate matrix/analyte or standard addition workflows when appropriate in order to monitor up or down regulation of naturally occurring endogenous species.

Established Biomarker Assays

  • Amino acids and linked pathways
  • Neurotransmitters and their metabolites (e.g. Norepinephrine, Dopamine, Serotonin, Acetylcholine, DOPAC, HVA, 5-HIAA)
  • Kynurenine pathway metabolites (e.g. Kynurenine, Quinolinic acid, 3-OH-Kynurenine, Kynurenic Acid. Adnthranilic Acid, Xanthurenic Acid)
  • Sphingolipids (e.g. Glucosyl vs. Galactosyl Ceramides, Ceramindes, Sphingosines, Lactosyl Ceramides, Gangliosides)
  • Glutamate and pyro-glutamate
  • Biphosphonates
  • TCA-cycle analytes
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Custom Biomarker Assays

Standalone, or multiplexed assays

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Method development, transfer and/or optimization

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Any Biological Matrix

We analyze any biofluid or tissue from any species

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